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What's the best route from St. Louis to Panama City?

I’m a senior at Saint Louis University. A group of my friends and I want to drive down to Panama City for spring break. We want to take the most direct route possible to enjoy the beach sooner rather than later. What’s the best way to get from St. Louis to Panama City?

avatar
Eric Schad · Updated on
Reviewed by Shannon Martin, Licensed Insurance Agent.
Is Panama City still the spring break capital of the country? You’ll have to find out for yourself. If you want to get to the Gulf shores of
Florida
quickly, the best route from
St. Louis
to
Panama City
includes only a few turns:
  • Take I-64 East (or 40 in St. Louis vernacular) to
    Mount Vernon
    , Illinois
  • Stay right at the sign for I-57 South
  • Keep cruising along until you reach Exit 44 for I-24 South toward Nashville
  • When you reach
    Nashville traffic
    , look for signs for I-65 South
  • Keep on I-65 until you reach Panama City
As with any spring break trip, stay safe! To build upon the idea of safety, you may also want to update your
car insurance
coverage with the
Jerry
app before you leave. You can find the right coverage at the right price, giving you a bit of extra cash for the best spring break ever.
Jerry is a licensed insurance broker and insurance comparison tool that collects quotes from over 55 top-rated insurers in just 45 seconds. After you find a great rate, Jerry can help you buy new insurance and cancel your old policy. Users save an average of $800+ per year!
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