What’s the best route from Knoxville to Asheville?

My partner and I are spending a long weekend in Asheville, and we want to get there as quickly as possible. What’s our best route from Knoxville?

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Answer provided by
Sarah Gray
Answered on May 24, 2022
The best route from Knoxville to Asheville is both quick and beautiful—just take I-40 the whole way.
Even though your whole route is on the interstate, you’ll be driving over or through:
Your trip will be a quick two hours over 115 miles, but much of it will be on a winding mountain highway, so be sure you’re ready for it by checking to see if your car insurance policy includes roadside assistance in case of a breakdown or accident.
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