What's the best route from Chicago to San Francisco?

Ever since I saw Full House, I’ve always wanted to see what San Francisco is all about. Now that my kids are grown and out of the house, I finally have time to make the trip. What’s the best driving route from Chicago to San Francisco?

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Answer provided by
Eric Schad
Answered on May 18, 2022
Full House is an American classic! So if you want to see the home from the show, also known as one of the Painted Ladies, you’ll have to embark on a 2,100-mile, 31-hour trip—the good news is that the best route from Chicago to San Francisco is just a straight shot west on I-80.
I-80 has a total length of 2,900 miles, so you’ll be going across a considerable distance. Along the way, you can also stop at these notable places:
  • The Quad Cities
  • Des Moines
  • Omaha
  • Cheyenne
  • Salt Lake City
  • Reno
  • Sacramento
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