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What’s the best route from California to South Carolina?

I’ll be making a cross-country road trip to South Carolina soon for a family reunion, and I want to pick a good route that’s not too complicated. What’s the best route from California to South Carolina?

avatar
Amber Reed · Updated on
Reviewed by Shannon Martin, Licensed Insurance Agent.
That’s quite a drive! In addition to seeing lots of family, you’ll also see a lot of the country on the way!
The best route from
California
 to
South Carolina
 is via I-40 East. This will comprise around 35 hours of driving, and the 2,400-odd miles will take you across the entire stretch of the southern United States.
As an added bonus, this route will take you part of the way along the famed Route 66. There’s a lot of
fun things to see
 on this route, so you might want to take some extra time to enjoy a piece of American road trip history!
Before you head out on any journey, take a few minutes to make sure you’re not paying too much for your
car insurance
. How? With
Jerry
, the comparison shopping
super app
!
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MORE:
All the road trip hacks you need to know!
TravelSouth CarolinaDriving TipsCalifornia
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