Traffic on Interstate 65 is usually pretty manageable, but there are definitely certain areas and times that see worse traffic than others! It’s usually best to avoid driving on I-65 from 6:00 AM to 9:00 AM and 5:00 PM to 7:00 PM as this is when traffic is at its highest.
Traffic is also often worse close to large cities along the interstate, such as:
If you’re commuting during these times or close to these cities, you should plan some extra time for your drive to make sure that you get to work on time.