Lexus RX 350 V6

The 2022 Lexus RX 350 V6 is a luxury SUV with 295 horsepower, 20 mpg city, and a 7.2-second 0 to 60 start time.
Written by Kate Kirby
Reviewed by Jessica Barrett
Updated on Mar 23, 2023
The Lexus RX 350 is a steal if you’re in the market for a midsized luxury SUV with great safety and tech features. It's equipped with a 295-hp engine, 7.2 seconds 0 to 60 start time, and a 20 mpg city fuel economy rate. 
Whether you’re venturing across the country or cruising around the city, the Lexus RX 350 is a top pick for its reliability and comfort. This midsized SUV has a powerful V6 engine which attracts drivers looking for a smooth ride, practicality, and luxury styling. 
In this guide, you'll find everything you need to know about the Lexus RX 350 V6. We’ll cover the performance metrics, fuel economy, and model comparisons for your Lexus. 
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2022 Lexus RX 350 V6

Starting price: $46,645
Engine: 3.5-liter V6
Horsepower: 295 hp @ 6300 rpm
Torque: 268 lb-ft @ 4700 rpm
0 to 60: 7.2 seconds 
The Lexus RX 350 V6 is a practical SUV that offers a smooth ride and plenty of great features. It comes in a range of colors, and there are five package upgrades available, including the cold weather package and the luxurious black line special edition. 
Here are more features that Lexus RX 350 drivers love:
  • Lexus Safety System+ 2.0: Features include Siri Eyes Free, lane-departure warning and intervention, front crash warning, automatic emergency brakes, adaptive cruise control, automatic high beams, and a rearview camera. 
  • Comfort and Convenience: Keyless ignition, adaptive cruise control, interior air filtration, and the leather interior make the RX 350 V6 a smooth ride. 
  • Infotainment, Bluetooth, and Navigation: Equipped with an 8-inch touchscreen, Apple CarPlay, WiFi hotspot, six USB ports, navigation, and more. 

How’s the fuel economy?

While the RX 350 has a great engine, it doesn’t stand up to other Lexus models when it comes to fuel efficiency. The
RX 450H
gets an impressive 31 mpg city and 28 mpg highway, while the RX 350 gets a moderate rating of 20 mpg city and 27 mpg highway

Which Lexus RX 350 models have the V6?

Lexus offers three trim levels, including the standard RX 350, the
F Sport
Appearance, and the F Sport Handling. All models come with the 3.5-liter V6 engine and feature varying upgrades. The F Sport Appearance has a starting cost of $49,050, while the F Sport Handling starts at $51,450.

How fast is the Lexus RX 350 V6? 

While the RX 350 is a practical and reliable car, it isn’t necessarily made for speed racing. All three trims have about the same 0 to 60 start time of between 6.8 seconds and 7.2 seconds.  
Here’s how similar luxury SUVs hold up against the RX 350: 
Key Takeaway All three trims of the Lexus RX 350 have a V6 engine, making it a reliable SUV with moderate ratings for speed and fuel economy.

Which is better: Lexus RX 350 vs. 450H?

Overall, the RX 350 and 450H are pretty similar vehicles. Both share V6 engines, a safety package, several tech features, and luxury finishes. The main difference lies in power and performance. The hybrid gets better fuel economy and has a powertrain that allows it to reach 308 horsepower, compared to the RX 350’s 295 horsepower. 
While the 450H does deliver some more improved specs than the 350, many find it difficult to justify the higher cost. Aside from saving some money on gas and a slightly more powerful engine, you’ll get nearly the same thing with the RX 350 and pay around $1,625 less
Whether you choose the RX 350 or the 450H, you’ll end up with a great SUV. If you’re looking to get the best deal, go with the 350; and if you’re looking for elevated performance, go with the 450H. 

How to find affordable Lexus RX 350 insurance

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