All You Need to Know About I-72

I-72 runs east to west between Illinois and Missouri.
Written by John Pickhaver
Reviewed by Jessica Barrett
Interstate 72, or I-72, covers just 179 miles along its east-to-west route from Champaign, Illinois to Hannibal, Missouri
I-72 only passes through two states, but that doesn’t mean it’s boring. There’s a lot you can see along this relatively short interstate. 
Ready to hit the road on your next trip between Illinois and
Missouri
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What is an interstate highway?

Interstates are highways that connect multiple states and/or metropolitan areas all across the US. Each interstate is given a number—usually one or two digits—so drivers can easily identify their route. 
East-west routes, like I-72, typically end in an even number, while north-south routes usually end in an odd number. And major interstates usually end in a zero or five—like I-10 or I-75.

What states does I-72 run through?

The I-72 runs through just two midwestern states: Illinois and Missouri. However, only 2.04 miles of I-72 are located in Missouri. The remaining 177.25 miles cross through Illinois.

Major interchanges on I-72

I-72 is a fairly peaceful drive. In fact, there are only two major connections and interchanges:
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Best places to eat along I-72

A road trip is only as good as the meals you have along the way. There are quite a few wonderful places to stop and eat along this Midwestern interstate. We’ve rounded up some of our favorites:
  • Biaggi's Ristorante Italiano
    (Champaign, IL): Chain outpost serving a large menu of Italian fare plus specialty cocktails in a laid-back setting.
  • Seven Saints
    (Champaign, IL): Stylish, wood-trimmed American tavern for creative burgers, craft beer, cocktails & wine.
  • Big Grove Tavern
    (Champaign, IL): Farm-to-table American fare, craft cocktails & regional beers in a modern space with rustic touches.
  • Jet's Palace
    (Hannibal, MO): Fresh Chinese dishes with a wide array of soups and appetizers to get you started. 
  • The Rebel Pig
    (Palmyra, MO): Full service BBQ joint with full menu and delicious daily specials.
Pro Tip: It is a good idea to make sure the restaurant is open! You don’t want to take a detour just to find out the place you’ve chosen is closed. 

What is there to do on I-72?

Though it only spans 179 miles, there’s still lots to see along 1-72. Here are a few places you might want to stop:

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